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Clinical trials for Case Finding

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    1,618 result(s) found for: Case Finding. Displaying page 1 of 81.
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    EudraCT Number: 2014-003087-20 Sponsor Protocol Number: 800_OPBG_2014 Start Date*: 2014-11-12
    Sponsor Name:IRCCS Ospedale Pediatrico Bambino Gesù
    Full Title: Determination of Plasmatic and CSF Levels Of High Doses Of Micafungin in Neonates Suffering from Systemic Candidiasis and/or Candida meningitis.
    Medical condition: Systemic Candidiasis and/or Candida Meningitis
    Disease: Version SOC Term Classification Code Term Level
    17.0 100000004862 10027238 Meningitis fungal NOS LLT
    17.0 100000004852 10027237 Meningeal fungal infections HLT
    17.0 100000004862 10042941 Systemic fungal infection NOS LLT
    Population Age: Preterm newborn infants, Newborns, Infants and toddlers, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2008-006765-82 Sponsor Protocol Number: MOXEP Start Date*: 2009-05-29
    Sponsor Name:ISTITUTO NAZIONALE DELLE MALATTIE INFETTIVE LAZZARO SPALLANZANI
    Full Title: Preventive therapy for multidrug-resistant tuberculosis: a multicentre clincal trial.
    Medical condition: Close contacts of an infectious respiratory of a MDR-TB who are diagnosed with tuberculosis infection that is likely to have been acquired from the MDR-TB case will be eligible for inclusion in th...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028440 HLGT
    9.1 10044756 HLT
    9.1 10021868 LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2012-004410-34 Sponsor Protocol Number: FOM_PER_1_12 Start Date*: 2013-01-11
    Sponsor Name:Cristina Peris Martínez
    Full Title: Influence of timolol maleate (ophthalmic gel 1 mg/g) on the keratometry and the parameters of corneal biomechanics in patients with keratoconus.
    Medical condition: Keratoconus
    Disease: Version SOC Term Classification Code Term Level
    14.1 10015919 - Eye disorders 10023353 Keratoconus PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2013-002562-39 Sponsor Protocol Number: CL2-78989-018 Start Date*: 2013-10-10
    Sponsor Name:Institut de Recherches Internationales Servier (IRIS)
    Full Title: An exploratory, open-label, single centre, phase II, proof of concept study of gevokizumab treatment in patients with Schnitzler syndrome.
    Medical condition: Schnitzler syndrome
    Disease: Version SOC Term Classification Code Term Level
    17.1 10040785 - Skin and subcutaneous tissue disorders 10062908 Schnitzler's syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2009-010116-15 Sponsor Protocol Number: CTU 052 D Start Date*: 2010-05-31
    Sponsor Name:RIEMSER Arzneimittel AG
    Full Title: A multicentre double blind placebo controlled clinical dose- finding study for three doses of Antiadipositum X 112 T® (Cathine-hydrochloride) vs. placebo in 240 patients with a body mass index (BMI...
    Medical condition: diet-related obesity diagnosed by BMI of 30 to 40 kg/m² or diet-related obesity diagnosed by BMI of 27 to 40 kg/m² in patient with coexisting risk factors like hyperlipidaemia, type 2 diabetes mell...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2017-001730-26 Sponsor Protocol Number: 205756 Start Date*: 2017-11-30
    Sponsor Name:Orchard Therapeutics (Europe) Ltd
    Full Title: A single arm, open label, clinical study of cryopreserved autologous CD34+ cells transduced with lentiviral vector containing human ARSA cDNA OTL-200, for the treatment of early onset Metachromatic...
    Medical condition: Metachromatic Leukodystrophy
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10067609 Metachromatic leukodystrophy PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-006086-17 Sponsor Protocol Number: 55005646 Start Date*: 2012-07-10
    Sponsor Name:Maria Fernanda Pedrero Escalas
    Full Title: "Effectiveness of homeopathic treatment (Agraphis nutans 5CH, Thuya occidentalis 5CH, Kalium muriaticum and Arsenicum iodatum 9CH 9CH) as adjuvant secretory otitis in children"
    Medical condition: Pediatric patients aged 2 months to 12 years presenting secretory otitis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10021881 - Infections and infestations 10033072 Otitis externa PT
    Population Age: Infants and toddlers, Children, Under 18 Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-024152-29 Sponsor Protocol Number: Start Date*: 2011-09-02
    Sponsor Name:University Hospital of Tübingen
    Full Title: Canakinumab for Behçet`s Disease Resistant to Standard Treatment (CanBeDisT)
    Medical condition: Behçet`s Disease
    Disease: Version SOC Term Classification Code Term Level
    14.0 10021428 - Immune system disorders 10004213 Behcet's syndrome PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2006-004748-22 Sponsor Protocol Number: ML20058 Start Date*: 2006-12-14
    Sponsor Name:AZIENDA OSPEDALIERA S. LUIGI GONZAGA
    Full Title: phase II study of the combination of bevacizumab plus somatostatin analogue and metronomic capecitabine as first-line therapy in patients with advanced inoperable well-differentiated neuroendrocri...
    Medical condition: Patients with Advanced Inoperable Well-Differentiated Neuroendocrine Tumors
    Disease: Version SOC Term Classification Code Term Level
    9.1 10057270 Neuroendocrine carcinoma LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007804-14 Sponsor Protocol Number: oxynorm 1 Start Date*: 2008-06-10
    Sponsor Name:Coombe Women's Hospital
    Full Title: A comparison of intravenous oxycodone with morphine in day-case laparoscopic gynaecological surgery
    Medical condition: Acute post-operative pain
    Disease: Version SOC Term Classification Code Term Level
    9.1 10066714 Acute pain LLT
    9.1 10036286 Post-operative pain LLT
    Population Age: Adults Gender: Female
    Trial protocol: IE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-005626-19 Sponsor Protocol Number: CVT-301-004E Start Date*: 2016-06-23
    Sponsor Name:Civitas Therapeutics, Inc.
    Full Title: A 12 Month, Dose-Level Blinded Study Investigating the Safety and Efficacy of CVT-301 (Levodopa Inhalation Powder) in Parkinson's Disease Patients With Motor Response Fluctuations (OFF Phenomena)
    Medical condition: Parkinson's Disease With Motor Response Fluctuations (OFF Phenomena)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004852 10034007 Parkinson's disease NOS LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed) ES (Completed)
    Trial results: View results
    EudraCT Number: 2013-002378-26 Sponsor Protocol Number: STRIX-MSext001 Start Date*: 2014-11-13
    Sponsor Name:Västerbottens Läns Landsting
    Full Title: Switch To RItuXimab in MS extension An extension study of STRIX-MS - a phase 2 open label study of Rituximab in MS patients previously treated with self-injectibles using a target based therapy app...
    Medical condition: The original trial (EudraCT 2010-023021-38) recruited 74 patients with relapsing-remitting multiple sclerosis in stable condition while treated with first line injectible disease-modifying drugs (D...
    Disease: Version SOC Term Classification Code Term Level
    16.0 10029205 - Nervous system disorders 10028245 Multiple sclerosis PT
    Population Age: Adults Gender: Male, Female
    Trial protocol: SE (Completed)
    Trial results: View results
    EudraCT Number: 2007-000179-41 Sponsor Protocol Number: 26051 Start Date*: 2008-09-11
    Sponsor Name:Mundipharma Research Ltd
    Full Title: Intrathecal chemotherapy with liposomal ara-C (Depocyte) in leptomeningeal metastases of solid tumors: a phase III study
    Medical condition: Leptomeningeal metastasis (LM) from solid tumors, in adult patients .
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024233 Leptomeningeal metastases LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Ongoing) GB (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-000880-26 Sponsor Protocol Number: HTX101-02G Start Date*: 2019-09-03
    Sponsor Name:Heidelberg ImmunoTherapeutics GmbH
    Full Title: A Randomized, Double-Blind, Double-Dummy Phase II Study of Single Dose HDIT101 versus Standard of Care Valaciclovir in Patients with Chronic Recurrent Anogenital HSV-2 Infection
    Medical condition: Chronic recurrent anogenital HSV-2 infection
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004862 10019938 Herpes genitalis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2006-001065-41 Sponsor Protocol Number: CSET 2006/1205 Start Date*: 2007-04-30
    Sponsor Name:Institut Gustave Roussy
    Full Title: Phase 2 single-arm studies of gemcitabine in combination with oxaliplatin in refractory and relapsed pediatric solid tumors
    Medical condition: refractory or relapsing malignant pediatric solid tumors
    Disease:
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: DE (Completed) IT (Completed) GB (Completed) NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2020-005226-28 Sponsor Protocol Number: D8110C00001 Start Date*: 2021-01-22
    Sponsor Name:AstraZeneca AB
    Full Title: A Phase III Randomized, Double-blind, Placebo-controlled Multicenter Study in Adults to Determine the Safety, Efficacy, and Immunogenicity of AZD1222, a Non-replicating ChAdOx1 Vector Vaccine, for ...
    Medical condition: SARS-COV-2 infection (COVID-19)
    Disease: Version SOC Term Classification Code Term Level
    23.0 10021881 - Infections and infestations 10051905 Coronavirus infection PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) DE (Completed) IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-004423-36 Sponsor Protocol Number: PTG-300-03 Start Date*: 2019-04-08
    Sponsor Name:Protagonist Therapeutics, Inc.
    Full Title: An Open Label Extension Study of PTG-300 in Non-Transfusion Dependent (NTD) and Transfusion-Dependent (TD) β-thalassemia Subjects
    Medical condition: β-Thalassemia Subjects with Chronic Anemia (transfusion and non transfusion dependent)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10043391 Thalassaemia beta PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GR (Completed) GB (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-015902-20 Sponsor Protocol Number: GHB-CS07 Start Date*: 2009-11-04
    Sponsor Name:AVIR Green Hills Biotechnology Research Development Trade AG
    Full Title: Randomized, double-blind, placebo-controlled, Phase IIa dose finding study of single dose GHB11L1 in healthy adults
    Medical condition: GHB-CS07 is a healthy volunteer trial. The intended indication for the investigational medicinal product (GHB11L1) is prevention of influenza A (H1N1).
    Disease: Version SOC Term Classification Code Term Level
    12.0 10022002 Influenza A virus infection LLT
    Population Age: Adults Gender: Male
    Trial protocol: AT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-012644-16 Sponsor Protocol Number: 361/09 Start Date*: 2009-07-24
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: PHASE 2 SINGLE- ARM STUDIES OF TEMOZOLOMIDE IN COMBINATION WITH TOPOTECAN IN REFRACTORY AND RELAPSED NEUROBLASTOMA AND OTHER PAEDIATRIC SOLID TUMOURS
    Medical condition: NEUROBLASTOMA AND OTHER PAEDIATRIC SOLID TUMOURS
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029260 PT
    9.1 10039491 PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-004988-27 Sponsor Protocol Number: FG-463-21-20 Start Date*: 2006-07-27
    Sponsor Name:Astellas Pharma BV
    Full Title: A PHASE II, MULTICENTRE, RANDOMISED, OPEN-LABEL, ACTIVE CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF MICAFUNGIN SALVAGE MONO THERAPY VERSUS ACTIVE CONTROL INTRAVENOUS SALVAGE MONO THE...
    Medical condition: Patients with haematopoietic stem cell transplantation (HSCT), acute leukaemia, myelodysplastic syndrome (MDS) and with proven (probable only in case of pulmonary aspergillosis) invasive aspergillo...
    Disease: Version SOC Term Classification Code Term Level
    8.1 10022881 Invasive bronchopulmonary aspergillosis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Prematurely Ended) BE (Completed) ES (Completed) HU (Completed) IT (Prematurely Ended)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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